Standard procedures were applied for reviewing the literature. Inclusion criteria were papers written in English or Spanish involving samples from Spanish-speaking Latin American individuals published until 2018. Methods: A systematic search of titles and abstracts in Medline, Biomed Central, Embase, Scopus, Scirus, PsycINFO, LILACS, and SciELO was conducted. Objectives: The aim of this study was to evaluate the validity of brief cognitive screening (BCS) tools designed to diagnose mild cognitive impairment (MCI) or dementia in Spanish-speaking individuals over the age of 50 years from Latin America (LA). 9Neurology Unit, Department of Medicine, Alemana Clinic, Universidad del Desarrollo, Santiago, Chile.8Memory and Neuropsychiatric Clinic (CMYN), Neurology Department, Del Salvador Hospital and University of Chile School of Medicine, Santiago, Chile.7Geroscience Center for Brain Health and Metabolism (GERO), University of Chile School of Medicine, Santiago, Chile.6Neuropsychology and Clinical Neuroscience Laboratory (LANNEC), Physiopathology Department, ICBM, Neurosciences and East Neuroscience Departments, University of Chile School of Medicine, Santiago, Chile.5Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru.4Neuromedicenter Adult Day Care Center, Quito, Ecuador.

3Neurology Department, Instituto Peruano de Neurociencias, Lima, Peru.

2Cognitive Decline and Dementia Diagnostic and Prevention Services Unit, Instituto Peruano de Neurociencias, Lima, Peru.1Research Unit, Instituto Peruano de Neurociencias, Lima, Peru.Nilton Custodio 1,2,3 * Lissette Duque 4 Rosa Montesinos 1,2 Carlos Alva-Diaz 5 Martin Mellado 6 Andrea Slachevsky 6,7,8,9 *

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